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  WORKSHOP  

Building a Centrosome

DATE: 10th - 13th March 2013
LOCATION: Wiston House, Steyning, West Sussex, UK
ORGANISERS:

Fanni Gergely
University of Cambridge, UK

David Glover
University of Cambridge, UK

The centrosome, a small organelle, is a key microtubule organising centre in cells. It is composed of a pair of cylindrical centrioles that are embedded in a protein-rich matrix. In each cell cycle the centrosome duplicates once and only once in a semi-conservative fashion much like the DNA in the nucleus.  Centrosomes play important roles both in cycling and non-cycling cells: in the former they participate in building the bipolar mitotic spindle, whereas in the latter they modulate the assembly of the primary cilium, a structure implicated in sensing and signalling. The presence of functional centrosomes is therefore important for cell physiology.

The last few years have seen an impressive increase in our knowledge and understanding of the biology of the centrosome, but many unanswered questions remain. Indeed, how does the cell actually build a centrosome? What are the regulatory pathways that ensure timely assembly of the new centrosome? Does the centrosome have different roles in symmetrically and asymmetrically dividing cells? Does the centrosome have specialised functions in different tissues? By inviting speakers with a wide range of expertise we aim to provide a multi-disciplinary forum that will facilitate exchange of ideas. We are confident that this exciting workshop will give fresh impetus to tackling outstanding questions related to centrosome biology.

Hover over images to see caption

Centrome
spindle

 

Download programme for this Workshop

Published Information from the Workshop

Meeting report written by Alexandre D. Baffet, Carol-Anne Martin, Ilaria Scarfone, Owen M. Daly, Ahuvit David, Alexandra Tibelius, Ramona Lattao, Muhammad S. Hussain and Jeffrey B. Woodruff and published in the Journal of Cell Science - http://jcs.biologists.org/content/126/15/3259.full.

JCS Executive Editor Sharon Ahmad’s interview with Jordan Raff at the Workshop - https://www.youtube.com/watch?v=QiLpFZq_uG0.

 


Workshop organisers = Fanni Gergely and David Glover

    ATTENDEES
 

Renata Basto
Institut Curie, Paris, France

 

Monica Bettencourt-Dias
IGC, Lisbon, Portugal

 

Michel Bornens
Institut Curie, Paris, France

 

Stephen Doxsey
University of Massachusetts, USA

 

Susan Dutcher
Washington University, St Louis, USA

 

Fanni Gergely
University of Cambridge, UK

 

David Glover
University of Cambridge, UK

 

Pierre Gonczy
EPFL, Lausanne, Switzerland

 

Cayetano Gonzalez
IRB, Barcelona, Spain

 

Gillian Griffiths
University of Cambridge, UK

 

Iain Hagan
University of Manchester, UK

 

Ingrid Hoffman
DKFZ, Heidelberg, Germany

 

Tony Hyman
Max Planck Institute, Dresden, Germany

 

Alexey Khodjakov
Wadsworth Center, New York, USA

 

Erich Nigg
University of Basel, Switzerland

 

Karen Oegema
University of California, San Diego, USA

 

David Pellman
Dana Farber Cancer Institute, Boston, USA

 

Jordan Raff
University of Oxford, UK

 

Ken Sawin
University of Edinburgh, UK

 

Elmar Schiebel
University of Heidelberg, Germany

 

Tim Stearns
Stanford University, California, USA

 

Richard Vallee
Columbia University, USA

 

Mark Winey
University of Colorado, Boulder, USA